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Enhanced formation of benzo(a)pyrene: DNA adducts in monocytes of patients with a presumed predisposition to lung cancer


Book ID
123145705
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
94 KB
Volume
2
Category
Article
ISSN
0169-5002

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Formation of dna adducts and water-solub
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Formation of DNA adducts and of water-soluble metabolites was studied in monocytes of 86 first-degree relatives of I 5 families. Tests were performed with blood monocytes using (G-3H)-benzo[a]pyrene as a model pro-carcinogen. Variance analysis revealed significantly higher inter-familial than intra-