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Formation of benzo(a)pyrene—DNA adducts in peripheral human lung tissue

✍ Scribed by Shinohara, Kunio; Cerutti, Peter A.


Book ID
122347184
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
440 KB
Volume
3
Category
Article
ISSN
0304-3835

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DNA adducts are mainly detected by 32 P-postlabeling and enzyme-linked immunosorbent assays. We have established a method for detection of benzo[a]pyrene-diol-epoxide (BPDE)-DNA adducts by flow cytometry, and have clarified the effects of the DNA adducts on cell-cycle progression and the relationshi