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Excisability and persistence of benzo(a)pyrene DNA adducts in epithelioid human lung cells

✍ Scribed by FELDMAN, GEORGE; REMSEN, JOYCE; SHINOHARA, KUNIO; CERUTTI, PETER


Book ID
109710506
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
346 KB
Volume
274
Category
Article
ISSN
0028-0836

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DNA adducts are mainly detected by 32 P-postlabeling and enzyme-linked immunosorbent assays. We have established a method for detection of benzo[a]pyrene-diol-epoxide (BPDE)-DNA adducts by flow cytometry, and have clarified the effects of the DNA adducts on cell-cycle progression and the relationshi