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Excision of benzo[a]pyrene diol epoxide I adducts from nucleosomal DNA of confluent normal human fibroblasts

✍ Scribed by M. Kaneko; P.A. Cerutti


Book ID
113136473
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
784 KB
Volume
38
Category
Article
ISSN
0009-2797

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DNA adducts are mainly detected by 32 P-postlabeling and enzyme-linked immunosorbent assays. We have established a method for detection of benzo[a]pyrene-diol-epoxide (BPDE)-DNA adducts by flow cytometry, and have clarified the effects of the DNA adducts on cell-cycle progression and the relationshi