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Encapsulation, pharmacokinetics and tissue distribution of interferon α-2b liposomes after intramuscular injection to rats

✍ Scribed by Hao Li; Li Yang; Gang Cheng; Hong-Yan Wei; Qun Zeng


Book ID
107642490
Publisher
Springer
Year
2011
Tongue
English
Weight
539 KB
Volume
34
Category
Article
ISSN
0253-6269

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The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated after intravenous (IV) and intramuscular (IM) injection of free MTX (treatment I), freshly prepared MTX-bearing positively charged liposomes (large unilamellar vesicles), PLUVs (treatment 11), and empty PLUVs mixed