Enantiospecific Synthesis of the Phospholipase A2 Inhibitors (-)-Cinatrin C1 and (+)-Cinatrin C3.
β Scribed by Anthony N. Cuzzupe; Romina Di Florio; Jonathan M. White; Mark A. Rizzacasa
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 80 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The synthesis of 2βaminoβ2βhydroxy[__3__β^__13__^__C__]naphthalene starting from 2β(1,3βdioxolanβ2βyl)βbenzyl chloride and sodium [^__13__^__C__]cyanide in seven preparative steps is reported. Diazotation of the labelled amino compound followed by deprotonation yields [__9a__β^__13__^__