𝔖 Bobbio Scriptorium
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Enantiospecific synthesis of polyhydroxy amino acids. Synthesis of the C33C38 portion of calyculins.

✍ Scribed by Ari M.P. Koskinen; Jingshan Chen


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
217 KB
Volume
32
Category
Article
ISSN
0040-4039

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A stereospecific synthesis of a potential Cl&Cl9 fragment of the novel antineoplastic macrolide amphidinolide-A is described. ## Amphidinolide-A (1) was isolated from dinoflagellate Amphidinium sp. by Kobayashi et. all. This compound has shown in v&-u activity against L1210 (I&j0 2.4 ng/mL) murin