𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Toward the synthesis of tetrodecamycin: asymmetric synthesis of a direct precursor of the C6C18 trans-decalin portion

✍ Scribed by Franz F Paintner; Gerd Bauschke; Kurt Polborn


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
196 KB
Volume
44
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


We report the asymmetric synthesis of a direct precursor of the C6 C18 trans-decalin portion of tetrodecamycin utilising an asymmetric intramolecular Diels-Alder (IMDA) reaction as the key step.


📜 SIMILAR VOLUMES


Asymmetric synthesis of the C(18)C(24)
✍ Marc Nowakowski; H.M.R Hoffmann 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 205 KB

The C(18)-C(24) segment of lasonolide A has been prepared with complete chemodifferentiation of functionality.

Strategy for the synthesis of the C10C1
✍ Stephen J. O'Connor; Paul G. Williard 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 255 KB

A stereospecific synthesis of a potential Cl&Cl9 fragment of the novel antineoplastic macrolide amphidinolide-A is described. ## Amphidinolide-A (1) was isolated from dinoflagellate Amphidinium sp. by Kobayashi et. all. This compound has shown in v&-u activity against L1210 (I&j0 2.4 ng/mL) murin