Studies directed toward the total synthesis of kabiramide C: Asymmetric synthesis of the C7–C19 fragment
✍ Scribed by Ping Liu; James S. Panek
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 221 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The synthesis of the C7-CI9 tris-oxazole li-agmenl 4 of kabiramide C via a BF~°OEt_~ promoted condensation between dimethyl acetal 12 and (S)-silane 6 as the crucial synthetic step is described.
📜 SIMILAR VOLUMES
An efficient synthesis of the CI-C6 aliphatic fragment 3 and its coupling to the C7-C19 fi'agment 4 of kabiramide C is described. Key transformations include a TiCI 4 promoted condensation
Studies Directed Toward the Total Synthesis of Scytophycin C: Synthesis of the C 1 -C 18 Fragment of Scytophycin C. -The synthesis of the C-1 to C-18 fragment (X) is based on a highly stereoselective carbon Ferrier-type rearrangement reaction of deoxyglucal (I) and the silyl enol ether (II). -(GRIEC