Enantioselective Synthesis of Phenyl-ethanolamines Through Application of Chiral Sulfoxide
โ Scribed by Sivakumar, Aathimanivelu V.; Lahoti, Anand M.; Bhat, Sujata V.
- Book ID
- 126795899
- Publisher
- Taylor and Francis Group
- Year
- 2009
- Tongue
- English
- Weight
- 253 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0039-7911
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## Abstract The sulfoxide mediated enantioselective reduction of carbonyl compounds was extended to the synthesis of enantiomerically pure syn and anti diols, including C~2~ symmetric diols. Several applications related to the syntheses of natural products are described. Finally, this sulfoxide med
Through Michael additionlacid induced cyclization of secondzuy amine to chiral acetylenic sulfoxide followed by Putnmerer cyclization, an approach to the enantioselective syntheses of pentacyclic yohimbine alkaloids is presented. O 1997Elsevier ScienceLtd.