ChemInform Abstract: Enantioselective Synthesis of Phenyl-ethanolamines Through Application of Chiral Sulfoxide.
β Scribed by Aathimanivelu V. Sivakumar; Anand M. Lahoti; Sujata V. Bhat
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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Chiral Acetylenic Sulfoxide in Enantioselective Synthesis of Yohimbine Alkaloid. -Michael addition of the secondary amine (I) to the chiral acetylenenic sulfoxide (II) followed by acid induced cyclization affords (III) as major product. It is a precursor of optically pure (IV), a known synthon of pe