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ChemInform Abstract: Asymmetric Synthesis of Chiral Sulfoxides

โœ Scribed by Henri B. Kagan


Publisher
John Wiley and Sons
Year
2009
Weight
11 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ W. OPPOLZER; O. FROELICH; C. WIAUX-ZAMAR; G. BERNARDINELLI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

The diastereomerically pure sulfinylating reagent (III) reacts with nucleophilic Grignard reagents or the zinc reagent derived from (VI) to yield chiral sulfoxides with excellent yields and enantioselectivities. Under specific conditions sequential reaction of (III) with LiN(Tms)2 followed by aldehy