ChemInform Abstract: Chiral Sulfoxides in Asymmetric Synthesis: Enantioselective Synthesis of (-)-(5S,7R)-Tarchonanthuslactone.
β Scribed by G. SOLLADIE; L. GRESSOT-KEMPF
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Chiral Acetylenic Sulfoxide in Enantioselective Synthesis of Yohimbine Alkaloid. -Michael addition of the secondary amine (I) to the chiral acetylenenic sulfoxide (II) followed by acid induced cyclization affords (III) as major product. It is a precursor of optically pure (IV), a known synthon of pe