Enantioselective synthesis of monofluorinated chiral building blocks from malonic acid
β Scribed by Ihara, Masataka; Kai, Tomoko; Taniguchi, Nobuaki; Fukumoto, Keiichiro
- Book ID
- 126306538
- Publisher
- Royal Society of Chemistry
- Year
- 1990
- Weight
- 177 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1472-7781
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π SIMILAR VOLUMES
methyl protecting groups (BBr,, CHCI,) then gave l a in 70 % yield. The 'H and 13C NMR spectra of 1 a (in D,O/ NaOD) and of 1 b (in CDC1,) reflect the symmetry of the molecules. The methoxyl groups are magnetically equivalent in 1 b, but in the open-chain triester precursor 2b, two
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract __N__βBoc protected amino acids of analogues of peptide nucleic add (PNA.), which are a class of conformationally constrained building blocks based on 4βaminoproline backbone with chirality at 2βC and 4βC, have been synthesized. Those monomers can be used for the construction of novel p