Diversity-Oriented Synthesis of Useful Chiral Building Blocks from D-Mannitol
β Scribed by Appu Aravind; Ponminor Senthil Kumar; Muthukumar Gomathi Sankar; Sundarababu Baskaran
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 707 KB
- Volume
- 2011
- Category
- Article
- ISSN
- 1434-193X
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## Abstract Enantiopure NβsulfinylβΞ΄βaminoβΞ²βketoesters and isoquinolones, prepared from sulfinimines (Nβsulfinyl imines) are a new class of polyfunctionalized chiral building blocks. These building blocks provide easy access to enantiomerically pure, functionalized piperidines and tetrahydroisoqui
## Abstract For Abstract see ChemInform Abstract in Full Text.
methyl protecting groups (BBr,, CHCI,) then gave l a in 70 % yield. The 'H and 13C NMR spectra of 1 a (in D,O/ NaOD) and of 1 b (in CDC1,) reflect the symmetry of the molecules. The methoxyl groups are magnetically equivalent in 1 b, but in the open-chain triester precursor 2b, two