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Synthesis of Aminocyclitols and Trihydroxylated Indolizidinone from a D-Mannitol-Derived Common Building Block

โœ Scribed by Preeti Gupta; A. P. John Pal; Y. Suman Reddy; Yashwant D. Vankar


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
710 KB
Volume
2011
Category
Article
ISSN
1434-193X

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## Abstract The enantiopure epoxides 2โ€“6 were synthesized from 1,2;5,6โ€diโ€Oโ€isopropylideneโ€Dโ€mannitol (1). The terminal epoxides 2 and 3 are available from the desoxy mannitol 9 in three steps. The __C__~2~โ€symmetrical epoxides 4 and 5 were generated via the Cโ€4โ€inverted alcohol 15. The __C__~2~โ€sy