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Synthesis of New Chiral Building Blocks for Novel Peptide Nucleic Acids

✍ Scribed by Wu Jie; Xu Xiao-Yu; Liu Ke-Liang

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 678 KB
Volume: 21
Category: Article
ISSN: 0256-7660
DOI: 10.1002/cjoc.20030210518

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✦ Synopsis

Abstract

N‐Boc protected amino acids of analogues of peptide nucleic add (PNA.), which are a class of conformationally constrained building blocks based on 4‐aminoproline backbone with chirality at 2‐C and 4‐C, have been synthesized. Those monomers can be used for the construction of novel peptide nucleic acid analogues.

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