Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecuar Stetter Reaction of Cyclohexadienones.
โ Scribed by Qin Liu; Tomislav Rovis
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 36 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
Dedicated to Professor Ronald Breslow on the occasion of his 80th birthday Scheme 1. Chiral NHC- [11,12] or enzyme-catalyzed [13] intermolecular asymmetric Stetter reactions. EWG = electron-withdrawing group, Ar = aromatic group, Het = heteroaromatic group, R = rest. Scheme 2. Proposed reaction path
An Enantioselective Synthesis of (-)-Allosamidin by Asymmetric Desymmetrization of a Highly Functionalized meso-Epoxide. -The enantioselective preparation of (XII) represents a formal total synthesis of (-)-allosamidin (XIII). A significant improvement compared to prior approaches affords this inte