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Enantioselective Organocatalytic Intramolecular Aza-Michael Reaction: a Concise Synthesis of (+)-Sedamine, (+)-Allosedamine, and (+)-Coniine

✍ Scribed by Fustero, Santos; Jiménez, Diego; Moscardó, Javier; Catalán, Silvia; del Pozo, Carlos


Book ID
111965821
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
97 KB
Volume
9
Category
Article
ISSN
1523-7060

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## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c