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ChemInform Abstract: Enantioselective Synthesis of 3H-Pyrrolo[1,2-a]indole-2-carbaldehydes via an Organocatalytic Domino Aza-Michael/Aldol Condensation Reaction.

✍ Scribed by Dieter Enders; Chuan Wang; Gerhard Raabe

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
41
Category
Article
ISSN
0931-7597

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## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c