Enantioselective hydrolysis of esters of secondary alcohols using lyophilized Bakers' yeast
✍ Scribed by B.I. Glänzer; K. Faber; H. Griengl; M. Röhr; W. Wöhrer
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 503 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0141-0229
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The enantioselectivity and yield of lipase-catalysed hydrolyses of epoxy butanoates (4) depends on R. Sharpless oxidation of the secondary allylic alcohol (8,R2=Pr) established that in the lipase-catalysed hydrolysis of (4,R2=Pr) the threo-isomer gave higher ee than the erythroisomer.
The utilization of enzymes is a recent achievement in organic synthesis. There are many good reasons for the organic chemist to consider this approach. Enzymatic reactions are very fast and specific. The same transformations carried out by classical means in several days or weeks, can be achieved in