Synthesis of chiral epoxy alcohols by use of baker's yeast
β Scribed by Mitsuhiro Takeshita; Nami Akutsu
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 238 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0957-4166
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π SIMILAR VOLUMES
Baker's yeast mediated reduction of the cc-acetoxy ketones (l)-( 2) proceeds with high enantio-and stereoselectivity to give the anti carbinols ($)-( 6), ea:ily converted into the masked chiral deoxy sugars ( 12)-( 14), --from which E-and k-deoxyzugars have been obtained. Carbohydrates are now bein
Two kinds of novel nitroalkene reductases were isolated from baker's yeast. Reduction of a trisubstituted nitroalkene by these reductases afforded the corresponding nitroalkane with excellent enantioselectivity, moderate diastereoselectivity, and in good yield.