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Enantioselective Highly Efficient Synthesis of (−)-Cephalotaxine Using Two Palladium-Catalyzed Transformations

✍ Scribed by Tietze, Lutz F.; Schirok, Hartmut


Book ID
119978862
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
192 KB
Volume
121
Category
Article
ISSN
0002-7863

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Highly Efficient Synthesis of Cephalotaxin by Two Palladium-Catalyzed Cyclizations. -The racemic intermediate (V) is converted with 75% yield by known procedures in 4 steps into the alkaloid cephalotaxin (VI), the parent compound of the antileukemic harringtonines. -(TIETZE,

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