โ Scribed by Pierre Duhamel; Jamal Jamal Eddine; Jean-Yves Valnot
No coin nor oath required. For personal study only.
O-&y active aLan& WM obtined by anymmtic one carbon A?UL~A~UL treaction. Va&i_ation 06 the natit 06 the imine moie.ty in the eMatiObdetiV& aLkyLa_tion 04 Schi.,jfj babe.4 de,tived dhom g.Lycine cawed the enavu%metLic Cicedb -to b&,(-t @om 0 -to 70 %. During the last few years, we have been concerned with enantioselective reactions (1) and in the course of this work we have envisaged a classification (2) of these reactions connected with an apparent ionic mechanism. For such reactions, we consider the three atoms (or group of atoms) involved chiral center formation. They can be chiral C
๐ SIMILAR VOLUMES
The highly stereoselective alkylation (% de=99.6 to 97.6) of a new chiral glycine enolate synthon derived from D-2-phenylglycinol is described. Deprotection of the alkylation adducts in a one-pot, three-step procedure provides the ethyl ester hydrochloride salts of the corresponding a-amino acids wi
emped Imine formodon between 3-hy.lmqcomphor and tetf. butyig3rinote led to & the substitudon pvducl al the 3-posidon. zinc-acetic acid tmotmenf of a offorded 3-acekuyomphor. Alkylodon of the imi~:e /mm from nmonphor and ten. buel @inare gave no stereosekcdon. Al@hztion of the iminefmm from IO-hydiq