Asymmetric PTC Alkylation of Glycine Imines: Variation of the Imine Ester Moiety.
✍ Scribed by Barry Lygo; Bryan Allbutt
- Book ID
- 101955034
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 131 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract For Abstract see ChemInform Abstract in Full Text.
O-&y active aLan& WM obtined by anymmtic one carbon A?UL~A~UL treaction. Va&i\_ation 06 the natit 06 the imine moie.ty in the eMatiObdetiV& aLkyLa\_tion 04 Schi.,jfj babe.4 de,tived dhom g.Lycine cawed the enavu%metLic Cicedb -to b&,(-t @om 0 -to 70 %. During the last few years, we have been concern
## Abstract For Abstract see ChemInform Abstract in Full Text.
In this paper we report an investigation into the possibility of effecting the asymmetric alkylation of glycine imines using chiral quaternary ammonium salt catalysts that are generated in situ. It is demonstrated that O-alkyl N-alkyldihydrocinchonidinium salts can be assembled from the parent alkal