A Convenient Method for Asymmetric Alkylation of Glycine Imine Esters Using Solid Supports.
โ Scribed by Haitao Yu; Hideko Koshima
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 86 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
a-Acetoxymethylpyrroles couple with a-free pyrroles in presence of Montmorillonite clay to form unsyrmnetrical pyrromethanes in excellent yields. Symmetrical pyrromethanes were also prepared in a similar manner by clay catalysed self-condensation of a-acetoxynmthylpyrroles.
The alkylation of N-Boc-N%-(2-chloroethyl)sulfamide 1 by electron-deficient alkyl bromides using the Mitsunobu reagent as mild base is described. This method was also applied to the N-glycosylation of various carbohydrates and was anomerically selective.