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Enantiomer separation of denopamine by capillary electrophoresis with charged and uncharged cyclodextrins

✍ Scribed by Kiyotaka Ishibuchi; Shin-ichi Izumoto; Dr. Hiroyuki Nishi; Tadashi Sato


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
492 KB
Volume
18
Category
Article
ISSN
0173-0835

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πŸ“œ SIMILAR VOLUMES


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## Abstract High resolution could be achieved for the enantiomers of acidic drugs, namely, sulindac, fenoprofen, ketoprofen, warfarin, and hexobarbital, in a buffer of pH 3 by the simultaneous addition of uncharged and charged β‐cyclodextrin derivatives. The interaction of the analytes with the ani

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A negatively charged cyclodextrin, sulfated ␀-cyclodextrin ␀-CD-Ž y . x SO , was used as a chiral selector for capillary electrophoresis separations of 4 4 basic pharmaceutical enantiomers. The charges of the basic enantiomers were controlled by adjusting the buffer pH. At pH 2.5, basic compounds a