Enantiomer separation of denopamine by capillary electrophoresis with charged and uncharged cyclodextrins
β Scribed by Kiyotaka Ishibuchi; Shin-ichi Izumoto; Dr. Hiroyuki Nishi; Tadashi Sato
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 492 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0173-0835
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π SIMILAR VOLUMES
## Abstract High resolution could be achieved for the enantiomers of acidic drugs, namely, sulindac, fenoprofen, ketoprofen, warfarin, and hexobarbital, in a buffer of pH 3 by the simultaneous addition of uncharged and charged Ξ²βcyclodextrin derivatives. The interaction of the analytes with the ani
A negatively charged cyclodextrin, sulfated β€-cyclodextrin β€-CD-Ε½ y . x SO , was used as a chiral selector for capillary electrophoresis separations of 4 4 basic pharmaceutical enantiomers. The charges of the basic enantiomers were controlled by adjusting the buffer pH. At pH 2.5, basic compounds a