Enantio-, Regio-, and Chemoselective Reduction of Aromatic α-Diketones by Baker’s Yeast
✍ Scribed by Nosrat O. Mahmoodi; Hussin G. Mohammadi
- Publisher
- Springer Vienna
- Year
- 2003
- Tongue
- English
- Weight
- 75 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0026-9247
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📜 SIMILAR VOLUMES
Optically pure \(\alpha\)-hydroxyketones and \(\alpha\)-diols are obtained through a regio- and stereocontrol of the reduction of acyclic \(\alpha\)-diketones by bakers' yeast. An investigation of the enzymatic system clearly demonstrates the role of two enzymes operating in sequence. An alcohol deh
Bakers' yeast reduction of 2-phenylthiocyclopentanone, 2-phenylthiocyclohexanone, and 2phenylthio-2-cyclopentenone affords the corresponding (lS,2R)-2-phenylthiocycloalkanols in optically pure form and excellent diastereomeric excess. Cyclic P-phenylthiocycloalkanols possess potentially versatile pr