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Diastereo- and enantio-selective reduction of 2-methyl-3-oxobutanoate by bakers' yeast

✍ Scribed by Kaoru Nakamura; Takehiko Miyai; Kenji Nozaki; Kazutoshi Ushio; Shinzaburo Oka; Atsuyoshi Ohno


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
139 KB
Volume
27
Category
Article
ISSN
0040-4039

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Enantioselective reduction of dialkyl 4-
✍ Chengye Yuan; Ke Wang; Jinfeng Li; Zuyi Li πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 120 KB πŸ‘ 1 views

## Abstract Dialkyl 4‐(dialkoxyphosphoryl)‐3‐oxobutanoates (**__1__**), upon yeast‐mediated bioreduction, afforded chiral dialkyl 4‐(dialkoxyphosphoryl)‐3‐hydroxybutanoates (**__2__**) in moderate to good yields and ee values. Significant improvement was reported for the preparation of dialkyl 4‐(d