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Emergence of YMDD motif mutant of hepatitis B virus during short-term lamivudine therapy in South Korea

โœ Scribed by Yong Han Paik; Hyo Young Chung; Wang-Shick Ryu; Kwan Sik Lee; Ji Sook Lee; Jung Hee Kim; Chun Kyun Lee; Chae Yoon Chon; Young Myoung Moon; Kwang-Hyub Han

Book ID
119526592
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
272 KB
Volume
35
Category
Article
ISSN
0168-8278

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Lamivudine is a potent inhibitor of hepatitis B virus (HBV) replication, but its long-term use may be associated with HBV tyrosine-methionine-aspartate-aspartate (YMDD) motif mutation. To examine the clinical features and course after emergence of YMDD mutants, 55 patients who received lamivudine th

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