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Rate of YMDD motif mutants in lamivudine-untreated Iranian patients with chronic hepatitis B virus infection

✍ Scribed by Amitis Ramezani; Ali Akbar Velayati; Mohammad Reza Hasanjani Roshan; Latif Gachkar; Mohammad Banifazl; Hossein Keyvani; Arezoo Aghakhani

Book ID: 118449307
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 138 KB
Volume: 12
Category: Article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2007.08.003

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Lamivudine is an effective antiviral agent for the treatment of chronic type B hepatitis. Recent studies have shown the appearance of lamivudine resistant viruses with mutations at the tyrosine-methionine-aspartate-aspartate (YMDD) motif of the viral polymerase in hepatitis B virus (HBV) infected pa