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Interferon therapy for flare-up of hepatitis B virus infection after emergence of lamivudine-induced YMDD motif mutant

✍ Scribed by Takashi Someya; Yoshiyuki Suzuki; Yasuji Arase; Masahiro Kobayashi; Fumitaka Suzuki; Akihito Tsubota; Satoshi Saitoh; Kazuaki Chayama; Naoya Murashima; Kenji Ikeda; Hiromitsu Kumada

Publisher
Springer Japan
Year
2001
Tongue
English
Weight
95 KB
Volume
36
Category
Article
ISSN
0944-1174

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## Abstract The pretherapy factors that could influence the emergence of resistant hepatitis B virus (HBV) tyrosine‐methionine‐aspartate‐aspartate (YMDD) motif mutants against lamivudine are not fully known in prolonged lamivudine therapy for hepatitis B e antigen (HBeAg)‐positive chronic hepatitis