✦ LIBER ✦

Electrospray negative ionization mass spectrometry of polyamides containing N-methylpyrrole and N-methylimidazole

✍ Scribed by Jun Wang; Jiang Zhou; G Yuan

Book ID: 102379542
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 73 KB
Volume: 40
Category: Article
ISSN: 1076-5174
DOI: 10.1002/jms.803

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✦ Synopsis

Electrospray negative ionization mass spectrometry of polyamides containing N-methylpyrrole and N-methylimidazole

Polyamides containing N-methylpyrrole (Py) and N-methylimidazole (Im) have attracted considerable attention from biological chemists because they can recognize and bind in the minor groove of DNA with high affinity and specificity. Furthermore these polyamides can permeate living cell membranes and have the potential to control specific gene expression. 1,2 We have previously Scheme 1. Main fragmentation models of the negative ion polyamides.

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