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Electron affinity and dipole moment of 1,2,4,5-tetraoxanes antimalarials and correlation with activity againstPlasmodium falciparum

✍ Scribed by de Paula, Mariane C.; Valle, Marcelo S.; Pliego, Josefredo R.


Book ID
125500578
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
461 KB
Volume
23
Category
Article
ISSN
1054-2523

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The structure and antimalarial activity
✍ Yuxiang Dong; Kevin J. McCullough; Sergio Wittlin; Jacques Chollet; Jonathan L. πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 266 KB

An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structures possess central tetraoxane rings with spiro-2,5-disubstituted cyclohexylidene substituents and 6-