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Einstufige Synthese von 17-Acetoxy-6-methyl-4,6-pregnadien-3,20-dion (Megestrolacetat) aus 17-Acetox-4-pregnen-3,20-dion

✍ Scribed by Annen, Klaus ;Hofmeister, Helmut ;Laurent, Henry ;Wiechert, Rudolf

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 122 KB
Volume: 1983
Category: Article
ISSN: 0947-3440
DOI: 10.1002/jlac.198319830421

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✦ Synopsis

A One‐step Synthesis of 17‐Acetoxy‐6‐methyl‐4,6‐pregnadiene‐3,20‐dione (Megestrol Acetate) from 17‐Acetoxy‐4‐pregnene‐3,20‐dione

Starting from 17‐Acetoxy‐4‐pregnene‐3,20‐dione (3), a one‐step synthesis of megestrol acetate (5) is described.

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