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Efficient synthesis of triazoles from d-arabinose and l-fucose

โœ Scribed by Timo Flessner; Chi-Huey Wong

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
71 KB
Volume
41
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

The efficient synthesis of sugar-derived triazoles via a one-pot substitution-cyclization-oxidation procedure is presented. Starting from D-arabinose and L-fucose, triazole structures as potential enzyme inhibitors were obtained in six to eight steps.

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## Abstract Lโ€Glucose derivatives are prepared by two different routes. The first involves a modification of the previously reported multiโ€step approach by __Shiozaki__^8^, starting from a Dโ€glucuronoโ€1,5โ€lactone derivative, resulting in the isolation of 2,3,4,6โ€tetraโ€__O__โ€benzylโ€Lโ€glucopyranose.