ChemInform Abstract: Efficient Large-Sca
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A. ZANKA
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Article
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2010
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John Wiley and Sons
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Efficient Large-Scale Synthesis of 4-Phenyl-3-butyn-2-one, a Key Intermediate for a Novel Potent Adenosine Antagonist. -A practical and facile large-scale synthesis of the 4-phenyl-3-butyn-2-one (IIIa) is presented based on the reaction of the in situ formed acetylenic Grignard reagent with two equ