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Efficient Large-Scale Synthesis of 4-Phenyl-3-butyn-2-one, a Key Intermediate for a Novel Potent Adenosine Antagonist

โœ Scribed by Zanka, Atsuhiko


Book ID
120077323
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
52 KB
Volume
2
Category
Article
ISSN
1083-6160

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ChemInform Abstract: Efficient Large-Sca
โœ A. ZANKA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Efficient Large-Scale Synthesis of 4-Phenyl-3-butyn-2-one, a Key Intermediate for a Novel Potent Adenosine Antagonist. -A practical and facile large-scale synthesis of the 4-phenyl-3-butyn-2-one (IIIa) is presented based on the reaction of the in situ formed acetylenic Grignard reagent with two equ