The effects of temporary water deprivation for 48 h on the pharmacokinetics and pharmacodynamics of bumetanide were examined after intravenous (i.v.) administration of bumetanide, 8mg kg-' to control and water deprived rats (n=7). The values of AUC, t,,, and MRT increased 79.0, 417, and 633 per cent
โฆ LIBER โฆ
Effects of water deprivation for 48 hours on the pharmacokinetics and pharmacodynamics of furosemide in rats
โ Scribed by M. J. Kang; W. H. Yoon; O. N. Kim; M. G. Lee
- Book ID
- 114738500
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 673 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0269-4727
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Effects of water deprivation on the phar
โ
Ji Y. Huang; Ok N. Kim; Sun H. Lee; Myung G. Lee
๐
Article
๐
1993
๐
John Wiley and Sons
๐
English
โ 667 KB
Pharmacokinetics of omeprazole in rats w
โ
Dae Y. Lee; Hyun S. Shin; Inchul Lee; Myung G. Lee
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 139 KB
๐ 2 views
Effects of phenobarbital and 3-methylcho
โ
Young M. Choi; So H. Kim; Myung G. Lee
๐
Article
๐
1991
๐
John Wiley and Sons
๐
English
โ 552 KB
Effects of water deprivation for 72 hour
โ
Soo K. Bae; Yu C. Kim; Jae K. Lee; Jong W. Kwon; Moohi Yoo; Inchul Lee; Myung G.
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 120 KB
๐ 1 views
Effects of water deprivation for 72 hour
โ
So Hee Kim; Jong Won Kwon; Won Bae Kim; Inchul Lee; Myung Gull Lee
๐
Article
๐
2002
๐
Elsevier Science
๐
English
โ 100 KB
Effects of water deprivation on the phar
โ
Young H. Choi; Inchul Lee; Myung G. Lee
๐
Article
๐
2007
๐
John Wiley and Sons
๐
English
โ 150 KB
๐ 2 views
## Abstract It was reported that metformin was mainly metabolized via hepatic CYP2C11, 2D1 and 3A1/2 in rats, and in a rat model of dehydration, the expressions of hepatic CYP2C11 and 3A1/2 were not changed. Hence, it could be expected that the __Cl__~nr~ of metformin is comparable between two grou