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Effects of rhubarb extract in rats with diabetic nephropathy

โœ Scribed by Takako Yokozawa; Li-Qun He; Yasuko Muto; Rika Nagasaki; Masao Hattori; Hikokichi Oura

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
76 KB
Volume
11
Category
Article
ISSN
0951-418X

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โœฆ Synopsis

Rhubarb extract was given orally to rats with diabetic nephropathy induced by subtotal nephrectomy and injection of streptozotocin. As a result, high blood and urinary glucose levels, which were conspicuous in similarly treated rats that were not given rhubarb extract, were ameliorated. Furthermore, improvement of hyperlipidaemia, and accelerated excretion of urinary urea nitrogen and creatinine were observed. These findings indicate that rhubarb extract has potential as a new therapeutic agent for inhibiting the progression of diabetic nephropathy.

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