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Effects of neocarzinostatin-chimeric Fab conjugates on the growth of human pancreatic carcinoma xenografts

โœ Scribed by Otsuji, E; Yamaguchi, T; Tsuruta, H; Yata, Y; Nishi, H; Okamoto, K; Taniguchi, K; Kato, M; Kotani, T; Kitamura, K


Book ID
109837246
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
903 KB
Volume
73
Category
Article
ISSN
0007-0920

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๐Ÿ“œ SIMILAR VOLUMES


Antitumor effect of neocarzinostatin con
โœ Eigo Otsuji; Toshiharu Yamaguchi; Yoshihiro Yata; Hiroshi Nishi; Kazuma Okamoto; ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 495 KB

The anticancer agent neocarzinostatin (NCS) was bound covalently to human/mouse chimeric Fab fragments of the monoclonal antibody A7 to form the conjugate chA7Fab-NCS. The antitumor effect of chA7Fab-NCS was tested by measuring the inhibition of 3H-thymidine incorporation into human pancreatic carci