Effects of morphine, nalorphine and pentobarbital alone and in combination on cerebral glycolytic substrates and cofactors of rats in vivo
β Scribed by Patrick W. Dodge; A.E. Takemori
- Book ID
- 115771379
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 576 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0006-2952
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Intraventricular administration of kainic acid at the dose of 0.1 pg induces a significant depression of rectal temperature followed rapidly by its slight elevation. Morphine (40.0 rag. kg-1 IP), which by itself elicited biphasic effect on the body temperature of rats-initially hypothermia followed
The effects of morphine (10 mg/kg), nalorphine (1 and 10 mg/kg), and naloxone (1 mg/kg) were studied on the neoeortical release of aeetylcholine (ACh) in midpontine pretrigeminal transected rats. Morphine and, to a lesser extent, nalorphine decreased ACh release. Naloxone was ineffective alone but a
## Abstract To quantitatively investigate the effects of pentobarbital anesthesia on brain activity, brain metabolite concentrations and cerebral metabolic rate of glucose, in vivo proton MR spectra, and electroencephalography were measured in the rat brain with various doses of pentobarbital. The