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Effects of morphine, nalorphine and naloxone on neocortical release of acetylcholine in the rat

✍ Scribed by John D. Matthews; Gaston Labrecque; Edward F. Domino

Publisher
Springer
Year
1973
Tongue
English
Weight
411 KB
Volume
29
Category
Article
ISSN
0033-3158

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✦ Synopsis

The effects of morphine (10 mg/kg), nalorphine (1 and 10 mg/kg), and naloxone (1 mg/kg) were studied on the neoeortical release of aeetylcholine (ACh) in midpontine pretrigeminal transected rats. Morphine and, to a lesser extent, nalorphine decreased ACh release. Naloxone was ineffective alone but antagonized the action of morphine.

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