๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effects of Intestinal and Hepatic Metabolism on the Bioavailability of Tacrolimus in Rats

โœ Scribed by Yukiya Hashimoto; Hiroaki Sasa; Masahiro Shimomura; Ken-ichi Inui


Book ID
110308058
Publisher
Springer US
Year
1998
Tongue
English
Weight
420 KB
Volume
15
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Hepatic and intestinal first-pass effect
โœ Soo K. Bae; Jin W. Kim; Young H. Kim; Yoon G. Kim; Sang G. Kim; Myung G. Lee ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 82 KB ๐Ÿ‘ 2 views

It was reported that the mean value of the extent of absolute oral bioavailability (F) of oltipraz at a dose of 20 mg/kg was 41.2% and only 2.68% of the oral dose was unabsorbed from the gastrointestinal tract in rats. Hence, the low F in rats could be due to considerable first-pass (gastric, intest

Comparative studies of the enhancing eff
โœ Hidetoshi Arima; Kiyokazu Yunomae; Kouzou Miyake; Tetsumi Irie; Fumitoshi Hiraya ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB ๐Ÿ‘ 1 views

The enhancing effects of cyclodextrins (CyDs) on the solubility, the dissolution rate, and the bioavailability of tacrolimus after oral administration to rats were examined and compared with those after administration of a PROGRAF 1 capsule containing the solid dispersion formulation of tacrolimus.