The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. UV C irradiation promotes SCE dose-dependent in the range of 0-40 mJ/cm2. No difference of this phenomenon may be observed, compairing young volunteers (20-40 year
Effects of dNTPs on the sister-chromatid exchange (SCE) frequency in human lymphocytes
β Scribed by Wanjin Xing
- Book ID
- 113194967
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 253 KB
- Volume
- 356
- Category
- Article
- ISSN
- 0027-5107
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π SIMILAR VOLUMES
The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. The addition of inorganic trivalent arsenic (Na2HAsO4) 10-6M and 2 x 10-6M induces a significant and dose-dependent increase of SCE. This phenomenon is as sensitiv
## Abstract The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation ass