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Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro

โœ Scribed by Andrea K. Robertson; Theresa M. Geiman; Umesh T. Sankpal; Gordon L. Hager; Keith D. Robertson


Book ID
116288987
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
808 KB
Volume
322
Category
Article
ISSN
0006-291X

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Dynamic expression of de novo DNA methyl
โœ Jian Feng; Hua Chang; En Li; Guoping Fan ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 889 KB

## Abstract To explore the role of DNA methylation in the brain, we examined the expression pattern of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the mouse central nervous system (CNS). By comparing the levels of Dnmt3a and Dnmt3b mRNAs and proteins in the CNS, we showed that Dnmt3b is det