Effect ofd-serine on the serotonin receptors of human platelets
β Scribed by Kaneez Fatima Shad
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 220 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0014-4819
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ro 11-2465, a cyanide derivative of imipramine with serotonin uptake inhibitory properties, was investigated in six healthy volunteers for its effect on serotonin concentration in blood platelets. The initial dose was 1 mg daily, the maximum dose of 3rag being reached on day 3 and maintained for 7 d
Inhibition (>80 per cent) of platelet monoamine oxidase (MAO-B type) and an increase of platelet serotonin content were observed after tranylcypromine administration. It is suggested that the increase in platelet serotonin reflects MAO-A inhibition, which may be correlated with antidepressant and hy