Effect of D-, M-, and T antagonists of serotonin on its uptake by human platelets
โ Scribed by G. F. Oksenkrug
- Publisher
- Springer US
- Year
- 1976
- Tongue
- English
- Weight
- 161 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ro 11-2465, a cyanide derivative of imipramine with serotonin uptake inhibitory properties, was investigated in six healthy volunteers for its effect on serotonin concentration in blood platelets. The initial dose was 1 mg daily, the maximum dose of 3rag being reached on day 3 and maintained for 7 d
A linear relationship was demonstrated between the reciprocals of the concentration of free hematoporphyrin and the moles of hematoporphyrin taken up by the platelet in the dark. Radiated platelets took up more hematoporphyrin than did controls; this increase in uptake was accounted for by the movem