✦ LIBER ✦

Effect of impaired renal function on tamoxifen

✍ Scribed by Carl M. Sutherland; Larry A. Sternson; James H. Muchmore; John E. Ball; Elmo J. Cerise

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 145 KB
Volume: 27
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930270404

No coin nor oath required. For personal study only.

✦ Synopsis

There is no information available in the literature on the blood levels of tamoxifen in patients with decreased renal function. As serious side effects of tamoxifen administered at high doses have been reported, a patient with decreased renal function and metastatic breast cancer was studied to determine the blood levels of tamoxifen while under therapy. Since no abnormally elevated levels of tamoxifen were found in this patient during the month of therapy, results of this study indicate that tamoxifen can be administered to patients with some degree of renal impairment without the risk of giving rise to abnormally elevated blood levels.

📜 SIMILAR VOLUMES

The effect of tamoxifen therapy on thyro

The effect of tamoxifen therapy on thyroid function tests

✍ Derek Gordon; Graham H. Beastall; Colin S. McArdle; John A. Thomson 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 296 KB 👁 2 views

The long-term effect of cisplatin on ren

The long-term effect of cisplatin on renal function

✍ Paul Fjeldborg; Jesper Sørensen; Poul E. Helkær 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB 👁 2 views

The long-term effect of cisplatin on renal function was studied in a follow-up investigation, 16 to 52 months after chemotherapy in 22 patients with disseminated nonseminomatous testicular cancer. The median cumulated cisplatin dose was 452 mg/m2 (range, 275-650 mg/m2). Prehydration with isotonic sa

Effect of acute water deprivation on ren

Effect of acute water deprivation on renal function in rats

✍ P. Prasad; S. Niazi; D. Jung 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 310 KB 👁 2 views

Effect of heparin-induced extracorporeal

Effect of heparin-induced extracorporeal lipoprotein apheresis on renal function

✍ Prem K.G. Chandran 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB 👁 1 views

During the course of heparin-induced extracorporeal lipoprotein apheresis, a patient with no prior known renal impairment or proteinuria demonstrated sustained improvement in estimated glomerular filtration rate, commensurate with reduction in serum lipids and creatine phosphokinase levels. Causes a

Effects of tamoxifen on blood coagulatio

Effects of tamoxifen on blood coagulation

✍ Martin J. Auger; Michael J. Mackie 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 340 KB 👁 2 views

Effect of tamoxifen on arterial microvas

Effect of tamoxifen on arterial microvascular anastomosis

✍ Breno Bezerra Gomes De Pinho Pessoa; Bruno Bezerra Menezes Cavalcante; Munique P 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

## Abstract Breast reconstruction after cancer treatment is based on the circulation of pedicle and microvascular flaps. This article aimed to verify the effect of tamoxifen (TMX) pretreatment in arterial anastomosis in rats. Twenty female Wistar rats were equally divided into two groups. TMX (0.3