## Abstract Mixed neuronal and nonneuronal cell cultures were obtained from 8βdayβold chick embryos cerebral hemispheres and glialβenriched cultures were obtained from fifteenβdayβold chick embryo cerebral hemispheres. Cultures were exposed to methadone, a narcotic drug, from days four to six. The
Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin
β Scribed by Hogan, Brigid; Shields, Robert; Curtis, David
- Book ID
- 123200010
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 480 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0092-8674
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## Abstract HTC cells incubated in the absence of serum for more than 14 hours have very low levels of ornithine decarboxylase, the first enzyme on the pathway of polyamine synthesis. Readdition of serum causes an increase in the activity of ODC, reaching a maximum on average 17 times above the bas
Sodium arsenite proved effective in preventing the induction of ornithine decarboxylase (ODC) activity elicited by dilution of Friend erythroleukemia cells in fresh medium. A 50 per cent inhibition was produced at approximately 1 p~ arsenite and complete inhibition was obtained at concentrations abo