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Cultured Hepatoma Cells for the Study of Enzyme Regulation: Induction of Ornithine Decarboxylase by Insulin and Asparagine

✍ Scribed by Van R. Potter, Theresa Ruh Evanson, Debra P. Gayda and James A. Gurr


Book ID
125616890
Publisher
Society for In Vitro Biology
Year
1984
Tongue
English
Weight
346 KB
Volume
20
Category
Article
ISSN
1475-2689

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## Abstract HTC cells incubated in the absence of serum for more than 14 hours have very low levels of ornithine decarboxylase, the first enzyme on the pathway of polyamine synthesis. Readdition of serum causes an increase in the activity of ODC, reaching a maximum on average 17 times above the bas